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  • 60 Consultation

  • 30 min Review & 30 min Consultation
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Akina Hoshino

Country: United States of America


Qualification: Ph.D. in Neuroscience; University of Maryland School of Medicine



Communication style

Experienced mentor, will speak slow in easy English, and has interacted with ESL researchers.


  1. Instructor profile
Akina is an experienced biomedical researcher and scientific editor. She has received several awards for her scholastic achievements and she has mentored students and researchers. Akina has conducted research at reputed organizations and she has affiliations with various societies. She is available for consultation sessions on topics related to academic writing and publishing. Akina is fluent in English and Japanese.
Education
  • Ph.D. Neuroscience – University of Maryland-Baltimore, School of Medicine 2006–2012
  • B.A. Biology and Chinese double major with honors – Vassar College 2002–2006
Editing and Writing Experience
  • Enago Academy – Consultant Apr 2018–present
  • Enago – Freelance editor (> 200,000 words edited) Jan 2017–present
  • Freelance editor for non-native English scientists in Japan Feb 2016–present
Research Experience
  • Continually employed in biomedical research (2006–present)
  • Funded on personal grant (2015–present)
Associated Achievements
  • 4 presentations at international conferences
  • Awarded the Knights Templar Eye Foundation Travel Award to attend the 2016 International Society for Eye Research Conference in Tokyo, Japan
  • Oral presentations at UW Program Project Grants and research update meetings
  • University of Maryland-Baltimore, Dept. of Neurobiology and Anatomy – Doctoral Thesis Sep 2006–Apr 2012
  • Edited grants, manuscripts, abstracts, posters, figures, and emails for colleagues, many of whom were mostly non-native English speakers (from Japan, Germany, Italy, China, India, and Argentina)
  • Published an E-book and 5 articles
  • Identified a novel neural anti-aggregant function for proSAAS
  • Developed cell death assays using Neuro2a cells to investigate the effects of proSAAS on Aβ1-42-induced cytotoxicity
  • Demonstrated additional modes of regulation — including self-association and peptide binding — of the peptide hormone processing enzyme, prohormone convertase 1/3,
Associated Achievements
  • Received Young Investigator Scholarships to attend the Alzheimer’s Drug Discovery Foundation conferences in 2009 and 2011
  • Oral and poster presentations at international conferences, NIH, UW, St. Jude Children’s Hospital, and UMB
  • Representative of the Neuroscience program and the Graduate Council in the Graduate Student Association
Publications
  • E-book: Akina Hoshino and Iris Lindberg. “Peptide Biosynthesis: Prohormone Convertases 1/3 and 2.” (L.D. Fricker & L. Devi, Eds). New Jersey: Morgan & Claypool Life Sciences Publishers. 2012
Peer-Reviewed Journals :
  • Nathaniel McVicar, Akina Hoshino, Anna La Torre, Thomas A. Reh, Walter L. Ruzzo, Scott Hauck. “FPGA acceleration of short read alignment.” Bioinformatics (In submission).
  • Chi Zhang, Wan-Qing Yu, Akina Hoshino, Jing Huang, Fred Rieke, Thomas A. Reh, Rachel O.L. Wong. “Development of ON and OFF cholinergic amacrine cells in the human fetal retina.” The Journal of Comparative Neurology. 2018 Feb 6.
  • Akina Hoshino*, Rinki Ratnapriya*, Matthew J. Brooks, Vijender Chaitankar, Matthew S. Wilken, Chi Zhang, Margaret R. Starostik, Linn Gieser, Anna La Torre, Mario Nishio, et al. “Molecular Anatomy of the Developing Human Retina.” Developmental Cell. 2017 Dec 18;43(6):763-779. (* indicates equal contribution)
  • Jennifer R. Chao, Deepak A. Lamba, Todd R. Klesert, Anna La Torre, Akina Hoshino, Russell Taylor, Anu Jayabalu, Abbi L. Engel, Thomas Khuu, Ruikang K. Wang, et al. “Transplantation of Human Embryonic Stem Cell-Derived Retinal Cells into the Subretinal Space of a Non-Human Primate.” Translational Vision Science & Technology. 2017 May 16; 6(3):4.
  • Anna La Torre, Akina Hoshino, Christopher Cavanaugh, Carol B. Ware and Thomas A. Reh. “The GIPC1-Akt1 pathway is required for the specification of the eye field in mouse embryonic stem cells.” Stem Cells 2015 Sep; 33(9):2674-85.
  • Akina Hoshino, Michael Helwig, Sina Rezaei, Casey Berridge, Jason L. Eriksen, and Iris Lindberg. “A novel function for proSAAS as an amyloid anti-aggregant in Alzheimer’s disease.” Journal of Neurochemistry 2014 Feb;128(3):419-30.
  • Michael Helwig, Akina Hoshino, Casey Berridge, Sang-Nam Lee, Nikolai Lorenzen, Daniel E. Otzen, Jason L. Eriksen, and Iris Lindberg. “The neuroendocrine protein 7B2 suppresses the aggregation of neurodegenerative disease-related proteins.” The Journal of Biological Chemistry 2013 Jan; 288:1114-1124
  • Akina Hoshino, Dorota Kowalska, François Jean, Claude Lazure, and Iris Lindberg. “Modulation of PC1/3 activity by self-interaction and substrate binding.” Endocrinology 2011 Apr; 152(4):1402-11
  • Leonardo Tonelli, Morgan Katz, Colleen Kovacsics, Todd Gould, Belzora Joppy, Akina Hoshino, Gloria Hoffman, Hirsh Komarow, and Teodor Postolache. “Allergic rhinitis induces anxiety-like behavior and altered social interaction in rodents.” Brain, Behavior, and Immunity 2009 Aug; 23(6):784-793
  • Leonardo Tonelli, Akina Hoshino, Morgan Katz, and Teodor Postolache. “Acute stress promotes aggressive-like behavior in rats made allergic to tree pollen.” International Journal of Child Health and Human Development 2008 Vol.1 305-311
Presentations
Invited presentations:
  • Akina Hoshino. “Using heterochronic cultures to speed up development.” University of Washington Institute for Stem Cell and Regenerative Medicine, Seattle, WA, December 2013
  • Akina Hoshino. “Regulation of prohormone convertase 1/3 and a novel function for proSAAS as a secretory chaperone.” National Institutes of Health, Bethesda, MD. September 2011
  • Akina Hoshino. “Regulation of prohormone convertase 1/3 and a novel function for proSAAS as a secretory chaperone.” University of Washington, Seattle, WA. September 2011
  • Akina Hoshino. “Regulation of prohormone convertase 1/3 and a novel function for proSAAS as a secretory chaperone.” St. Jude Children’s Hospital, Memphis, TN. August 2011
  • Akina Hoshino. “Regulation of the peptide hormone-synthesizing enzyme, prohormone convertase 1/3 (PC1/3).” University of Maryland-Baltimore, Baltimore, MD. Protease Interest Group. March 2011
Posters:
  • Akina Hoshino, Chi Zhang, Rinki Ratnapriya, Raunak Sinha, Zhou Yu, Dennis M. Dacey, Olivia Bermingham-McDonogh, Anand Swaroop, Fred Rieke, Rachel O.L. Wong, and Thomas A. Reh. “Characterization of human fetal retinal development: from genes to function.” Allen Frontiers Symposium. San Francisco, CA. October 2017
  • Akina Hoshino, Rinki Ratnapriya, Chi Zhang, Rachel O.L. Wong, Anand Swaroop, and Thomas A. Reh. “Immunohistochemical and transcriptome analyses of the developing human fetal retina.” Biennial Meeting of the International Society for Eye Research. Tokyo, Japan. September 2016
  • Chi Zhang, Akina Hoshino, Thomas Reh, Rachel Wong, and Dennis Dacey. “Connectomic reconstruction suggests refinement of foveal midget circuitry in the developing human retina.” FASEB Conference on Retinal Neurobiology and Visual Processing. Keystone, CO. July 2016
  • Akina Hoshino, Chi Zhang, Rachel Wong, and Thomas A. Reh. “Characterization of inner retinal neuron development in the human fetal fovea.” Annual Meeting of the Association for Research in Vision and Ophthalmology. Seattle, WA. May 2016
  • Chi Zhang, Wan-Qing Yu, Akina Hoshino, Thomas A. Reh. And Rachel O. L. Wong. “Topographic distributions and maturation of starburst amacrine cells in the fetal human retina.” Annual Meeting of the Association for Research in Vision and Ophthalmology. Seattle, WA. May 2016
  • Akina Hoshino, Anna La Torre, Lauren E. Hood, and Thomas A. Reh. “The role of miRNAs in the developmental timing of human fetal retina and embryonic stem cell-derived retina.” Society for Neuroscience Annual Meeting. Washington DC, November 2014
  • Anna La Torre, Akina Hoshino, Lauren E. Hood, Thomas A. Reh. “MicroRNAs play essential roles during stem cell differentiation into retinal populations.” 5th NIGMS Workshop in pluripotent stem cell research. National Institutes of Health, Bethesda, MD. March 2014
  • Akina Hoshino, Michael Helwig, Casey Berridge, Jason Eriksen, and Iris Lindberg. “Structure-function analysis of proSAAS as an Aβ1-42 anti-aggregant.” Program in Neuroscience Annual Retreat. Baltimore, MD. June 2011
  • Akina Hoshino, Michael Helwig, Sang-Nam Lee, and Iris Lindberg. “The neuroendocrine proteins proSAAS and 7B2 prevent Aβ1-42 aggregation.” Society for Neuroscience Annual Meeting. San Diego, CA. November 2010
  • Iris Lindberg, Dorota Kowalska, and Akina Hoshino. “Prohormone convertase 1/3 activity and stability is affected by self-interaction.” Gordon Conference, Proteolytic Enzymes and Their Inhibitors. Lucca, Italy. May 2010
  • Akina Hoshino, Dorota Kowalska, and Iris Lindberg. “Self-aggregation and interaction with binding proteins affect prohormone convertase 1/3 stability.” Society for Neuroscience Annual Meeting. Chicago, IL. October 2009
  • Akina Hoshino, Dorota Kowalska, and Iris Lindberg. “Stabilizing factors of Prohormone Convertase 1.” Graduate Research Conference. Baltimore, MD. April 2009
  • Akihiko Ozawa, Ernestine Lee, Akina Hoshino, Robert Halenbeck, Joseph Miceli, Tracy Mandichak, Srinivas Kothakota, and Iris Lindberg. “Validation of novel peptide hormones using prohormone convertase screening.” ASBMB New Orleans, LA. March 2009
Awards and Scholarship
  • Knights Templar Eye Foundation Travel Award for International Society for Eye Research Sept 2016
Conference
  • NRSA-NEI F32 Individual Postdoctoral Fellowship Sept 2015–present
  • 12th Alzheimer’s Drug Discovery Foundation (ADDF) Young Investigator Scholarship Sept 2011
  • 10th Alzheimer’s Drug Discovery Foundation (ADDF) Young Investigator Scholarship Sept 2009
  • Professor Anita Zerzoli Scholarship Endowment 2005–2006
Languages
  • Fluent in English and Japanese
Membership and Services
  • International Society for Eye Research 2016–present
  • Association for Research in Vision and Ophthalmology 2015–present
  • Society for Neuroscience 2009–present
  • Graduate Student Association – Graduate Council Representative 2010–2011
  • Graduate Student Association – Program in Neuroscience Representative 2008–2011

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