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  • 30 Consultation


  • 60 Consultation

  • 30 min Review & 30 min Consultation
    ※Online consultation will be in the latter 30 minutes.
    ※Please send the manuscript by 2-5 days prior to the date of the session(consult@enago.com)

Michael Spurlock

Country: United States of America


Qualification: Ph.D. in Nutritional Biochemistry (University of Missouri; USA)



Communication style

Experienced mentor, will speak slow in easy English, and has interacted with ESL researchers.


  1. Instructor profile
Michael is an award-winning researcher who has published over 50 papers in peer-reviewed journals. He has served as a primary reviewer for the U.S. Food & Drug Administration (FDA) and has received multiple awards/honors for various scholastic contributions. Michael is also engaged in a leadership role at a prominent North American university.
Michael would be glad to share research consultation on the following:
  • Veterinary medicine projects involving IGF-1, leptin, interleukins, etc.
  • Animal-model-based studies on obesity, inflammation, and cancer
This expert is offering specialized consultation in the following areas: Drafting Manuscripts, Selecting Journals, Earning Citations, Handling Journal Rejection, Understanding Research Ethics, Selecting Research Topics, Networking in Conferences, Managing References, Postdoctoral/Academic Job Interviews, Peer Review Process, and other related topics. Education
  • B.S., Animal Science; University of Missouri
  • M.S., Nutritional Biochemistry; University of Missouri. Dr. J. E. Savage, Thesis advisor
  • Ph.D., Nutritional Biochemistry; Collateral Fields in Histology and Molecular Biology; University of Missouri. Dr. Boyd L. O’Dell, Dissertation advisor
Professional Appointments:
  • Postdoctoral Research Associate, University of Missouri, 1989-1990.
  • Primary Reviewer, U.S. Food & Drug Administration, Center for Veterinary Medicine, 1990-1991.
  • Postdoctoral Research Associate, Purdue University, 1991-1993.
  • Research Scientist, Purina Mills, Inc., 1993-1994.
  • Senior Research Scientist, Purina Mills, Inc., 1994-1996.
  • Research Manager, Purina Mills, Inc., 1997-1998.
  • Senior Research Manager, Purina Mills, Inc., 1998-1999.
  • Adjunct Assistant Professor, Purdue University, 1995-1999.
  • Assistant Professor, Purdue University, Department of Animal Sciences, 1999-2002.
  • Associate Professor, Purdue University, Department of Animal Sciences, 2002-2005
  • Professor, Purdue University, Department of Animal Sciences, 2005.
  • Associate Professor, Iowa State University, Department of Human Nutrition and Department of
  • Animal Science, 2005-2007
  • Chair, Nutritional Sciences Council, Iowa State University, 2008-2010
  • President, Midwestern Section, American Society of Animal Science, 2008-2009
  • Professor, Iowa State University, Department of Food Science & Human Nutrition and Department of Animal Science, 2008-2015
  • Virginia M. Gladney Professor, Nutritional Sciences, Iowa State University, Department of Human Nutrition and Department of Animal Science, 2010-2013
  • Director, Integrated and Translational Research, Nutrition & Wellness Research Center, Iowa State University, 2010-2013
  • Director of Graduate Education, Nutritional Sciences, Iowa State University, 2013-2014
Awards & Honors
  • National Pork Producers' Council, Innovative Basic Research Award, 1994.
  • National Pork Producers' Council, Innovative Basic Research Award, 1997.
  • School of Agriculture Nominee, David and Lucille Packard Research Fellowship Competition, Purdue University, 2003.
  • ESCOP/ACOP Leadership Fellow, 2003-04.
  • Purdue University, College of Agriculture Outstanding Research Award, 2004.
  • Outstanding Faculty Research Development Award, Iowa State University, 2007
  • Virginia M. Gladney Professorship, Nutritional Sciences, Iowa State University, 2010-2014.
  • American Society of Animal Science, Growth & Development Research Award, 2011
Professional Publications in Scientific (peer-reviewed) Journals: (select entries)
  • Ajuwon, K.M., et al., Interleukin-6 and interleukin-15 are selectively regulated by lipopolysaccharide and interferon-gamma in primary pig adipocytes. Am J Physiol Regul Integr Comp Physiol, 2004. 286(3): p. R547-53.
  • Ajuwon, K.M., et al., Chronic leptin administration increases serum NEFA in the pig and differentially regulates PPAR expression in adipose tissue. J Nutr Biochem, 2003. 14(10): p. 576-83.
  • Ajuwon, K.M., et al., The regulation of IGF-1 by leptin in the pig is tissue specific and independent of changes in growth hormone. J Nutr Biochem, 2003. 14(9): p. 522-30.
  • Ajuwon, K.M. and M.E. Spurlock, Palmitate activates the NF-kappaB transcription factor and induces IL-6 and TNFalpha expression in 3T3-L1 adipocytes. J Nutr, 2005. 135(8): p. 1841-6.
  • Ajuwon, K.M. and M.E. Spurlock, Adiponectin inhibits LPS-induced NF-kappaB activation and IL-6 production and increases PPARgamma2 expression in adipocytes. Am J Physiol Regul Integr Comp Physiol, 2005. 288(5): p. R1220-5.
  • Ajuwon, K.M. and M.E. Spurlock, Direct regulation of lipolysis by interleukin-15 in primary pig adipocytes. Am J Physiol Regul Integr Comp Physiol, 2004. 287(3): p. R608-11.
  • Boddicker, N., et al., Effects of ad libitum and restricted feeding on early production performance and body composition of Yorkshire pigs selected for reduced residual feed intake. Animal, 2011. 5(9): p. 1344-53.
  • Boddicker, N., et al., Effects of ad libitum and restricted feed intake on growth performance and body composition of Yorkshire pigs selected for reduced residual feed intake. J Anim Sci, 2011. 89(1): p. 40-51.
  • Boddicker, R.L., et al., Early lesion formation in colorectal carcinogenesis is associated with adiponectin status whereas neoplastic lesions are associated with diet and sex in C57BL/6J mice. Nutr Cancer, 2011. 63(8): p. 1297-306.
  • Boddicker, R.L., et al., Low-dose dietary resveratrol has differential effects on colorectal tumorigenesis in adiponectin knockout and wild-type mice. Nutr Cancer, 2011. 63(8): p. 1328-38.
  • Davis, J.E., et al., Absence of Tlr2 protects against high-fat diet-induced inflammation and results in greater insulin-stimulated glucose transport in cultured adipocytes. J Nutr Biochem, 2011. 22(2): p. 136-41.
  • Davis, J.E., et al., The c-Jun N-terminal kinase mediates the induction of oxidative stress and insulin resistance by palmitate and toll-like receptor 2 and 4 ligands in 3T3-L1 adipocytes. Horm Metab Res, 2009. 41(7): p. 523-30.
  • Davis, J.E., et al., Tlr-4 deficiency selectively protects against obesity induced by diets high in saturated fat. Obesity (Silver Spring), 2008. 16(6): p. 1248-55.
  • Debinski, M., et al., Intracoronary adiponectin at reperfusion reduces infarct size in a porcine myocardial infarction model. Int J Mol Med, 2011. 27(6): p. 775-81.
  • Dilger, A.C., et al., Myostatin null mice respond differently to dietary-induced and genetic obesity. Anim Sci J, 2010. 81(5): p. 586-93.
  • Faris, R.J., et al., Inflammation in response to n3 fatty acids in a porcine obesity model. Comp Med, 2012. 62(6): p. 495-503.
  • Gabler, N.K., et al., Feeding long-chain n-3 polyunsaturated fatty acids during gestation increases intestinal glucose absorption potentially via the acute activation of AMPK. J Nutr Biochem, 2009. 20(1): p. 17-25.
  • Gabler, N.K., et al., In utero and postnatal exposure to long chain (n-3) PUFA enhances intestinal glucose absorption and energy stores in weanling pigs. J Nutr, 2007. 137(11): p. 2351-8.
  • Gabler, N.K., et al., n-3 PUFA attenuate lipopolysaccharide-induced down-regulation of toll-like receptor 4 expression in porcine adipose tissue but does not alter the expression of other immune modulators. J Nutr Biochem, 2008. 19(1): p. 8-15.
  • Gabler, N.K. and M.E. Spurlock, Integrating the immune system with the regulation of growth and efficiency. J Anim Sci, 2008. 86(14 Suppl): p. E64-74.
  • Houseknecht, K.L., et al., The biology of leptin: a review. J Anim Sci, 1998. 76(5): p. 1405-20.
  • Houseknecht, K.L., et al., Expression and cDNA cloning of porcine peroxisome proliferator-activated receptor gamma (PPARgamma). Gene, 1998. 225(1-2): p. 89-96.
  • Houseknecht, K.L., et al., Growth hormone regulates leptin gene expression in bovine adipose tissue: correlation with adipose IGF-1 expression. J Endocrinol, 2000. 164(1): p. 51-7.
  • Houseknecht, K.L. and M.E. Spurlock, Leptin regulation of lipid homeostasis: dietary and metabolic implications. Nutr Res Rev, 2003. 16(1): p. 83-96.
  • Jacobi, S.K., et al., Cloning and expression of porcine adiponectin, and its relationship to adiposity, lipogenesis and the acute phase response. J Endocrinol, 2004. 182(1): p. 133-44.
  • Jacobi, S.K., et al., Adipocytes, myofibers, and cytokine biology: new horizons in the regulation of growth and body composition. J Anim Sci, 2006. 84 Suppl: p. E140-9.
  • Ji, S., et al., Myostatin expression in porcine tissues: tissue specificity and developmental and postnatal regulation. Am J Physiol, 1998. 275(4 Pt 2): p. R1265-73.
  • Ji, S., et al., Soybean isoflavones, genistein and genistin, inhibit rat myoblast proliferation, fusion and myotube protein synthesis. J Nutr, 1999. 129(7): p. 1291-7.
  • Ji, S., et al., Partial cloning and expression of the bovine leptin gene. Anim Biotechnol, 1998. 9(1): p. 1-14.
  • Ji, S.Q., et al., Porcine somatotropin improves growth in finishing pigs without altering calpain 3 (p94) or alpha-actin mRNA abundance and has a differential effect on calpastatin transcription products. J Anim Sci, 1998. 76(5): p. 1389-95.
  • Ji, S.Q., et al., Proinflammatory cytokines regulate myogenic cell proliferation and fusion but have no impact on myotube protein metabolism or stress protein expression. J Interferon Cytokine Res, 1998. 18(10): p. 879-88.
  • Leininger, M.T., et al., Leptin expression is reduced with acute endotoxemia in the pig: correlation with glucose, insulin, and insulin-like growth factor-1 (IGF-1). J Interferon Cytokine Res, 2000. 20(1): p. 99-106.
  • Leininger, M.T., et al., Physiological response to acute endotoxemia in swine: effect of genotype on energy metabolites and leptin. Domest Anim Endocrinol, 2000. 18(1): p. 71-82.
  • Mao, G., et al., Effect of a mitochondria-targeted vitamin E derivative on mitochondrial alteration and systemic oxidative stress in mice. Br J Nutr, 2011. 106(1): p. 87-95.
  • Mao, G., et al., A mitochondria-targeted vitamin E derivative decreases hepatic oxidative stress and inhibits fat deposition in mice. J Nutr, 2010. 140(8): p. 1425-31.
  • McComb, M.A. and M.E. Spurlock, Expression of stress proteins in porcine tissues: developmental changes and effect of immunological challenge. J Anim Sci, 1997. 75(1): p. 195-201.
  • McCracken, B.A., et al., Weaning anorexia may contribute to local inflammation in the piglet small intestine. J Nutr, 1999. 129(3): p. 613-9.
  • Mills, S.E., M.E. Spurlock, and D.J. Smith, Beta-adrenergic receptor subtypes that mediate ractopamine stimulation of lipolysis. J Anim Sci, 2003. 81(3): p. 662-8.
  • Miner, J.L., et al., Expression and complement d activity of porcine adipsin. Protein Expr Purif, 2001. 23(1): p. 14-21.
  • Park, S.K., et al., Chronic activation of 5'-AMP-activated protein kinase changes myosin heavy chain expression in growing pigs. J Anim Sci, 2009. 87(10): p. 3124-33.
  • Raman, P., S.S. Donkin, and M.E. Spurlock, Regulation of hepatic glucose metabolism by leptin in pig and rat primary hepatocyte cultures. Am J Physiol Regul Integr Comp Physiol, 2004. 286(1): p. R206-16.
  • Spurlock, M.E., Regulation of metabolism and growth during immune challenge: an overview of cytokine function. J Anim Sci, 1997. 75(7): p. 1773-83.
  • Spurlock, M.E., et al., Nutritionally induced adipose hypertrophy in young pigs is transient and independent of changes in the expression of the obese and peroxisome proliferator activated receptor genes. J Nutr Biochem, 2002. 13(2): p. 112-120.
  • Spurlock, M.E., et al., The effect of ractopamine on beta-adrenoceptor density and affinity in porcine adipose and skeletal muscle tissue. J Anim Sci, 1994. 72(1): p. 75-80.
  • Spurlock, M.E., J.C. Cusumano, and S.E. Mills, The affinity of ractopamine, clenbuterol, and L-644,969 for the beta-adrenergic receptor population in porcine adipose tissue and skeletal muscle membrane. J Anim Sci, 1993. 71(8): p. 2061-5.
  • Spurlock, M.E., J.C. Cusumano, and S.E. Mills, (-)-[3H]-dihydroalprenolol binding to beta-adrenergic receptors in porcine adipose tissue and skeletal muscle membrane preparations. J Anim Sci, 1993. 71(7): p. 1778-85.
  • Spurlock, M.E., et al., Obese gene expression in porcine adipose tissue is reduced by food deprivation but not by maintenance or submaintenance intake. J Nutr, 1998. 128(4): p. 677-82.
  • Spurlock, M.E., et al., Effect of dietary energy source and immunological challenge on growth performance and immunological variables in growing pigs. J Anim Sci, 1997. 75(3): p. 720-6.
  • Spurlock, M.E. and N.K. Gabler, The development of porcine models of obesity and the metabolic syndrome. J Nutr, 2008. 138(2): p. 397-402.
  • Spurlock, M.E., K.J. Hahn, and J.L. Miner, Regulation of adipsin and body composition in the monosodium glutamate (MSG)-treated mouse. Physiol Behav, 1996. 60(5): p. 1217-21.
  • Spurlock, M.E., et al., Regulation of PPARgamma but not obese gene expression by dietary fat supplementation. J Nutr Biochem, 2000. 11(5): p. 260-6.
  • Spurlock, M.E., et al., Changes in the expression of uncoupling proteins and lipases in porcine adipose tissue and skeletal muscle during feed deprivation*(1). J Nutr Biochem, 2001. 12(2): p. 81-7.
  • Spurlock, M.E., et al., Leptin expression in porcine adipose tissue is not increased by endotoxin but is reduced by growth hormone. J Interferon Cytokine Res, 1998. 18(12): p. 1051-8.
  • Spurlock, M.E. and J.E. Savage, Effect of dietary protein and selected antioxidants on fatty liver hemorrhagic syndrome induced in Japanese quail. Poult Sci, 1993. 72(11): p. 2095-105.
  • Spurlock, M.E. and J.E. Savage, Research note: antioxidant activity of Japanese quail liver cytosol in the absence and presence of reduced glutathione. Poult Sci, 1992. 71(5): p. 928-31.
  • Wang, X., et al., Effects of triacylglycerol structure and solid fat content on fasting responses of mice. Eur J Nutr, 2015.
  • Weber, T.E., B.J. Kerr, and M.E. Spurlock, Regulation of hepatic peroxisome proliferator-activated receptor alpha expression but not adiponectin by dietary protein in finishing pigs. J Anim Physiol Anim Nutr (Berl), 2008. 92(5): p. 569-77.
  • Weber, T.E. and M.E. Spurlock, Leptin alters antibody isotype in the pig in vivo, but does not regulate cytokine expression or stimulate STAT3 signaling in peripheral blood monocytes in vitro. J Anim Sci, 2004. 82(6): p. 1630-40.
  • Wulster-Radcliffe, M.C., et al., Adiponectin differentially regulates cytokines in porcine macrophages. Biochem Biophys Res Commun, 2004. 316(3): p. 924-9.

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