Stephen M. Beckstrom-Sternberg
Qualification:
PhD 1988, Claremont Graduate University - Botany
Communication style
Experienced mentor, will speak slow in easy English, and has interacted with ESL researchers.
- Instructor profile
分子生物学や植物学、バイオインフォマティクスなど複数の分野で20以上の第一著者論文の発表経験がある。学部生、大学院生の生物学コースで15年以上教鞭を取っている。アメリカ合衆国農務省(USDA)やアメリカ国立衛生研究所(NIH)など著名な助成機関から13年間助成を受けた経験も。学会での多数の論文発表や、書籍出版、ウェブサイトやオンラインデータベースの構築も行ってきた。
難解な研究プロジェクトの進行や論文準備に限らず、助成金の申請や著名ジャーナルへの投稿、バイオインフォマティクスのツール開発などの相談に対応可能。
その他の経歴
- 様々な学会や要件に応じた編集、フォーマット調整を行った経験
- 説得力のある言葉選びや文法、文章構成に精通
- 分子生物学とバイオインフォマティクスの領域を専門とし、最先端の技術にも通じている。したがって、応用バイオテクノロジー関連の相談にも対応可能。
- 40を超える論文、ポスターの作成経験。
以下の研究領域に特化した相談にも対応可能。
- 分子生物学
- バイオインフォマティクス
- 植物学
- ゲノミクス
Academic Positions
- 2016–Present: Adjunct Professor. Scottsdale Community College (SCC), USA
- 2017: Adjunct Professor. Park University, USA
- 2003–2016: Associate Professor. Norther Arizona University, USA
- 2003–2011: Senior Investigator. Translational Genomics Research Institute (TGen), Phoenix, USA
- 2002–2003: Associate Investigator. Genome Technology Branch/ National Human Genome Research Institute (NHGRI), National Institutes of Health (NIH), Bethesda, MD, USA
- 1997–2003: Co-Director, Bioinformatics Group, NIH Intramural Sequencing Center (NISC), National
- Institutes of Health, USA
- 1996–2005: President, Star Mountain Enterprises, Inc., USA
- 1994–1997: Faculty Research Associate, University of Maryland, USA
- 1994–1996: Research Scientist, Economic Botany, National Germplasm Resources Laboratory, U.S. Department Of Agriculture
- 1992–1993: Consultant, Protein Analysis, Large Scale Biology, Corp., Rockville, USA
- 1991–1994: Postdoctoral Scientist, Economic Botany, National Germplasm Resources Laboratory, U.S. Department Of Agriculture, USA
- 1991: Lecturer, Biology, California State University, USA
- 1988–1991: Postdoctoral Scientist, Molecular Systematics, Rancho Santa Ana Botanic Garden, USA
Awards
- 2005: Northern Arizona University/College of Engineering and Natural Sciences Faculty Travel Award
- 2002: National Human Genome Research Institute Merit Award
- 1998: National Institutes of Health (NIH) Director's Award
Education
- 1988: Ph.D. Claremont Graduate University - Botany (Dissertation: Molecular Systematics of the Centrospermae: Studies Using 2-D PAGE)
- 1981: Master of Sciences, University of California, Riverside - Botany
- 1979: Bachelor of Sciences, University of California, Riverside - Plant Science
Publications
- Sahl Jason W, Beckstrom-Sternberg Stephen M, Babic-Sternberg James, et.al. (2015). The In Silico Genotyper (ISG): an open-source pipeline to rapidly identify and annotate nucleotide variants for comparative genomics applications. bioRXiv. doi: http://dx.doi.org/10.1101/015578. (not peer reviewed)
- Khmaladze Ekaterina, Birdsell Dawn N, Naumann Amber A, …, Beckstrom-Sternberg Stephen M, et.al. (2014). Phylogeography of Bacillus anthracis in the country of Georgia shows evidence of population structuring and is dissimilar to other regional genotypes. PLos One 9(7):e102651.
- Gopaul Krishna K, Sells Jessica, Lee Robin, Beckstrom-Sternberg Stephen M, Foster Jeffrey T, and Whatmore Adrian M. (2014). Development and application of a multiplex High Resolution Melting assay as a tool for the rapid single-tube identification of five significant Brucella species. BMC research notes 7:903. doi: 10.1186/1756-0500-7-903.
- Baltrus DA, Dougherty K, Beckstrom‐Sternberg SM, Beckstrom‐Sternberg JS, & Foster JT. (2014). Incongruence between MLSA and whole genome based phylogenies: Pseudomonas syringae pathovar pisi as a cautionary tale. Molecular plant pathology 15(5):461-465.
- Wattam Alice, Foster Jeffrey, Mane Shrinivasrao, Beckstrom-Sternberg Stephen, et.al. (2014). Comparative phylogenomics and evolution of the Brucellae: A path to virulence. J Bacteriology 196(5):920-930. doi: 10.1128/JB.01091-13.
- Busch Joseph, Van Andel Roger, Stone Nathan, …, Beckstrom-Sternberg Stephen, et.al. (2013). The innate immune response may be important for surviving plague in wild Gunnison’s prairie dogs. Journal of Wildlife Diseases 49(4): 920-931.
- Price Erin P, Sarovich Derek S, Mayo Mark, …, Beckstrom-Sternberg Stephen M, et.al. (2013). Within-host evolution of Burkholderia pseudomallei over a twelve-year chronic carriage infection. mBio 4(4): e00388-13. doi: 10.1128/mBio.00388-13.
- Pearson,Talima, Hornstra Heidie M, Schaack Sarah, Schupp James M, Beckstrom-Sternberg Stephen M, et.al. (2013) When outgroups fail; phylogenomics of the emerging pathogen, Coxiella burnetii. Systematic biology 62(5): 752–762. doi: 10.1093/sysbio/syt038.
- Amy J Vogler, Fabien Chan, Roxanne Nottingham, ..., Stephen M Beckstrom-Sternberg, et.al. (2013) A decade of plague in Mahajanga, Madagascar: insights into the global maritime spread of pandemic plague. mBio 4(1):e00623-12. doi: 10.1128/mBio.00623-12.
- Price EP, Seymour ML, Sarovich DS, …, Beckstrom-Sternberg SM, et.al. (2012) Molecular epidemiologic investigation of an anthrax outbreak among heroin users, Europe. Emerg Infect Dis. 18(8):1307-13. doi: 10.3201/eid1808.111343.
- Foster JT, Price LB, Beckstrom-Sternberg SM, et.al. (2012) Genotyping of Brucella species using clade specific SNPs. BMC Microbiol 12(1):110.
- Price EP, Dale JL, Cook JM, …, Beckstrom-Sternberg SM, et.al. (2012) Development and Validation of Burkholderia pseudomallei-Specific Real-Time PCR Assays for Clinical, Environmental or Forensic Detection Applications. PloS one 7(5):e37723. Epub 2012 May 18.
- Searcy BT, Beckstrom-Sternberg SM, Beckstrom-Sternberg JS, et.al. (2012) Thyroid hormone-dependent development in Xenopus laevis: A sensitive screen of thyroid hormone signaling disruption by municipal wastewater treatment plant effluent. Gen Comp Endocrinol 176(3):481-92. Epub 2012 Jan 11. http://dx.doi.org/10.1016/j.ygcen.2011.12.036.
- Gyuranecz M, Birdsell DN, Splettstoesser W, Beckstrom-Sternberg SM, et.al. (2012) Phylogeography of Francisella tularensis subsp. holarctica, Europe. Emerg Infect Dis 18(2): 290–293 doi: 10.3201/eid1802.111305.
- Okinaka R, Price E, Wolken S, …, Beckstrom-Sternberg S, et.al. (2011) An Attenuated Strain of Bacillus anthracis (CDC 684) has a Large Chromosomal Inversion and Altered Growth Kinetics. BMC Genomics 12:477 doi:10.1186/1471-2164-12-477.
- Vogler AJ, Chan F, Wagner DM, ..., Beckstrom-Sternberg, SM, et.al. (2011) Phylogeography and Molecular Epidemiology of Yersinia pestis in Madagascar. PLoS Negl Trop Dis. 5(9): e1319. doi:10.1371/journal.pntd.0001319.
- Engelthaler DM, Bowers J, Scupp JA, ..., Beckstrom-Sternberg SM, et.al. (2011) Molecular investigations of a locally acquired case of melioidosis in Southern AZ, USA. PLoS Negl Trop Dis 5(10): e1347. doi:10.1371/journal.pntd.0001347
- Gravel S, Henn BM, Gutenkunst RN, ..., The 1000 Genomes Project (…, Beckstrom-Sternberg, SM,…), Bustamante, CD. (2011) Demographic history and rare allele sharing among human populations. PNAS 108(29):11983-11988. doi: 10.1073/pnas.1019276108.
- Rivarola M, Foster JT, Chan AP, …, Beckstrom-Sternberg SM, et.al. (2011) Castor bean organelle genome sequencing and worldwide genetic diversity analysis. PLoS One 6(7):e21743. Epub 2011 Jul 7.
- Chanturia G, Birdsell DN, Kekelidze M, …, Beckstrom-Sternberg SM, et.al. (2011) Phylogeography of Francisella tularensis subspecies holarctica from the country of Georgia. BMC Microbiol 11:139. PubMed PMID: 21682874.
- Engelthaler David M, Chiller Tom, Schupp James A, Colvin Joshua, Beckstrom-Sternberg Stephen M, et.al. (2011) Next-Generation Sequencing of Coccidioides immitis Isolated during Cluster Investigation. Emerging Infectious Diseases 17(2) February 2011 [serial on the Internet]. http://wwwnc.cdc.gov/eid/article/17/2/10-0620_article. doi: 10.3201/eid1702.100620.
- Robbins CM, Tembe WA, Baker A, …, Beckstrom-Sternberg S, et.al. 2010. Copy Number and Targeted Mutational Analysis Reveals Novel Somatic Events in Metastatic Prostate Tumors. Genome Research 21:47-55. doi: 10.1101/gr.107961.110.
- The 1000 Genomes Project Consortium (…, Beckstrom-Sternberg SM,… et al.). (2010) A map of human genome variation from population-scale sequencing. Nature 467(7319):1061-1073. http://www.nature.com/nature/journal/v467/n7319/abs/nature09534.html. doi: 10.1038/nature09534.
- Losada L, Ronning CM, DeShazer D, ..., Beckstrom-Sternberg S, et.al. (2010) Continuing evolution of Burkholderia mallei through genome reduction and large-scale rearrangements. Genome Biology and Evolution 2:02. doi:0.093/gbe/evq003.
- Sheff KW, York E, Driebe E, …, Beckstrom-Sternberg SM, et.al. (2010) Development of a Rapid, Cost-Effective TaqMan Real-Time PCR Assay for Identification and Differentiation of Coccidioides immitis and Coccidioides posadasii. Med. Mycology 48(3): 466-469.
- Trunck LA, Propst KL, Wuthiekanun V, Tuanyok A, Beckstrom-Sternberg SM, et.al. (2009) Molecular Basis of Rare Aminoglycoside Susceptibility and Pathogenesis of Burkholderia pseudomallei Clinical Isolates from Thailand. PLoS Neglected Trop Dis 3(9): e519.
- Pearson T, Giffard P, Beckstrom-Sternberg S, et.al. (2009) Phylogeographic reconstruction of a bacterial species with high levels of lateral gene transfer. BMC Biology 7:78 doi: 10.1186/1741-7007-7-78.
- Vogler AJ, Birdsell D, Price LB, Bowers JR, Beckstrom-Sternberg SM, et.al. (2009) Phylogeography of Francisella tularensis: global expansion of a highly fit clone. J Bacteriol 191(8):2474-84. Epub 2009 Feb 27.
- Foster JT, Beckstrom-Sternberg SM, Pearson T, et.al. (2009) Whole-genome-based phylogeny and divergence of the genus Brucella. J Bacteriol 191(8):2864-70. Epub 2009 Feb 6.
- Tuanyok Apichai, Leadem Benjamin R, Auerbach Raymond K, Beckstrom-Sternberg Stephen M, et.al. (2008) Genomic islands from five strains of Burkholderia pseudomallei. BMC Genomics 9:566. doi: 10.1186/1471-2164-9-566
- Beckstrom-Sternberg SM, Auerbach RK, Godbole S, et.al. (2007). Complete genomic characterization of a pathogenic A.II strain of Francisella tularensis subspecies tularensis. PLoS ONE 2 (9):e947.
- Touchman JW, Wagner DM, Hao J, …, Beckstrom-Sternberg SM, Keim P. A. (2006). North American Yersinia pestis genome sequence: SNPs and phylogenetic analysis. PLoS ONE 2(2):e220. doi:10.1371/journal.pone.0000220.
- Payne-Jackson A, Beckstrom-Sternberg S. (2005) Traditional remedies – Legacy from the past – implications for the future. Pp. 50-77. In: YN Clement, and CE Seaforth, eds. Advancing Caribbean herbs in the 21st century – II. Proceeding of the seventh international workshop on herbal medicine in the Caribbean.
- Lei B, Morris DP, Smith MP, …, Beckstrom-Sternberg SM, et.al. (2005) Novel human 1a-adrenoceptor single nucleotide polymorphisms alter receptor pharmacology and biological function. Naunyn-Schmiedeberg’s Archives of Pharmacology 371(3):229-39.
- JW Thomas, JW Touchman, RW Blakesley, GG Bouffard, SM Beckstrom-Sternberg, et.al. (2003) Comparative analyses of multi-species sequences from targeted genomic regions. Nature 424:788-793.
- JW Thomas, MG Schueler, TJ Summers, …, SM Beckstrom-Sternberg, NISC Comparative Sequencing Program, & ED Green. (2003) Pericentromeric Duplications in the Laboratory Mouse. Genome Research 13(1):55-63.
- U DeSilva, L Elnitski JR Idol, …, SM Beckstrom-Sternberg, et.al. (2002) Generation and comparative analysis of ~3.3 mb of mouse genomic sequence orthologous to the region of human chromosome 7q11.23 implicated in Williams Syndrome. Genome Research 12:3-15.
- PJ Blackshear, WS Lai, JM Thorn, …, SM Beckstrom-Sternberg, et.al. (2001) The NIEHS Xenopus Maternal EST Project: interim analysis of the first 13,879 ESTs from unfertilized eggs. Gene 267:71-87.
- H Lowe, A Payne-Jackson, SM Beckstrom-Sternberg, and JA Duke. (2000) Jamaica's ethnomedicine: It's potential in the health care system, University Press of the West Indies, Jamaica.
- Ellsworth RE, DC Jamison, JW Touchman, …, SM Beckstrom-Sternberg, et.al. (2000) Comparative genomic sequence analysis of human and mouse cystic fibrosis transmembrane conductance regulator genes. PNAS 97(3):1172-1177.
- Touchman, J.W., Y. Anikster, NL Dietrich, …, SM Beckstrom-Sternberg, WA Gahl, and ED Green. (2000) The encompassing the nephropathic cystinosis gene (CTNS): complete sequencing of a 200-kb segment and discovery of a novel gene within the common cystinosis-causing deletion. Genome Research 10:165-173.
- Beckstrom-Sternberg, SM and DC Jamison. (1999) Using the Agricultural Genome Information System. In: Bioinformatics Databases and Systems, Ch. 14, (S. Letovsky, ed.), Kluwer.
- Duke, JA, J. duCellier, and S Beckstrom-Sternberg. (1997) Western Herbal Medicine: Materia Medica. in: Schoen, AM, Wynn, S.G, eds. "Complementary and Alternative Veterinary Medicine", Chap. 19, Unit 5, Botanical Medicine. Mosby (publisher)
- Beckstrom-Sternberg, SM, G Juvik, D Bigwood, et.al. (1996) Plant molecular biology. In: Internet for the molecular biologist. Horizon Sci. Press, London.
- Beckstrom-Sternberg, SM, and JA Duke. (1996) CRC handbook of medicinal mints (Aromathematics). CRC Press, Boca Raton, FL.
- Beckstrom-Sternberg, SM and JA Duke. (1994) Potential for synergistic action for phytochemicals in spices. Pp. 201-223. In: G. Charalambous, ed. Herbs, spices and edible fungi. Elsevier Science Publications, Amsterdam.
- Duke, JA and SM Beckstrom-Sternberg. (1994) "Acceptable" levels of flavoring ingredients? Pp. 741-757. In: G. Charalambous, ed. Herbs, spices and edible fungi. Elsevier Science Publications, Amsterdam.
- Beckstrom-Sternberg, SM. (1993) Utility of the PHYTOCHEMECO database. Pp. 267-286. In: K. Downum, J. Romeo, and H. Stafford, eds. Phytochemical potential of tropical plants. Plenum Press, New York.
- Beckstrom-Sternberg, SM, LH Rieseberg, and K Doan. (1991) Gene lineage analysis in populations of Helianthus niveus and H. petiolaris (Asteraceae). Plant Syst Evol 195: 125-138.
- Rieseberg, LH, SM Beckstrom-Sternberg, A Liston, and D Arias. (1991) Phylogenetic and systematic inferences from chloroplast DNA and isozyme variation in Helianthus section Helianthus (Asteraceae). Syst Bot 16:50-76.
- Rieseberg, LH, SM Beckstrom-Sternberg, and K Doan. (1990) Helianthus annuus ssp. texanus has chloroplast DNA and nuclear ribosomal RNA genes of Helianthus debilis ssp. cucumerifolius. Proc. Natl. Acad. Sci. USA 87:593-597.
- Beckstrom-Sternberg, SM. (1989) Two-dimensional gel electrophoresis as a taxonomic tool: Evidence from the Centrospermae. Biochem. Syst Ecol 17:573-582.
- Beckstrom-Sternberg, SM. (1988) Molecular systematics of the Centrospermae: Studies using two-dimensional gel electrophoresis. Ph.D. thesis. Claremont Graduate School: Claremont, CA.