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Vassiliki Fotaki

居住地: Edinburgh, UK


学歴: Ph.D. in Biological Sciences (Molecular Biology, Genetics and Neuroscience) University of Barcelona, Barcelona, Spain



コミュニケーションスタイル

ESL(英語が母国語でない)研究者との交流経験がある。平易な英語をゆっくり話す。


  1. 対応可能な相談内容
生物医学の分野にて並行実施する共同研究プロジェクトの設計、計画、実行の経験は15年以上。また、中枢神経系障害、眼科、血液腫瘍学を含む複数の治療学にも幅広い知識を有する。優れた学術ライティングスキルがあり、10以上の助成金獲得、900回以上引用された20以上の論文発表、および影響力の大きい医療従事者向け教育プログラム実施の経験。 相手に合わせた柔軟、かつ丁寧なコミュニケーションを得意とし、口頭およびポスター発表の経験も豊富。主要な関係者が研究者や医療従事者であっても、一般人であっても、発表のスタイルや内容を聞き手のニーズに合わせられる。 主な業績:
  • 研究プログラムおよび多様な研究チームを率いた経験
  • 教育資材の開発や興味深いセミナー、講演、チュートリアルの実施(受講者からの好意的なフィードバックを得ている)
  • 神経科学の学術雑誌およびGACR(チェコの科学財団)での審査委員会における専門家としての学術的洞察の提供
医学、科学論文の執筆に限らず、口頭およびポスター発表の相談に適任。 上記に加えて、以下の具体的な相談にも対応可能。
  • 眼科
  • 血液腫瘍学
Academic Positions
    • 2002–2012   Biomedical Research Scientist, University of Edinburgh, Centre for Integrative Physiulogy
    • 2012 – June 2017   Principal Investigator, University of Edinburgh, Centre for Integrative Physiulogy
Other Positions
      • 2017-2018  Scientific and Medical Education Specialist, Myeloma UK
Education
      • 2002    Ph.D. in Biulogical Sciences (Mulecular Biulogy, Genetics and Neuroscience), University of Barcelona, Spain
      • 1995    B.Sc. (Hons) in Biulogy (Honours dissertation in Human Mulecular Genetics) University of Athens, Athens, Greece
Publications
      • Smith R, Huang YT, Tian T, Vojtasova D, Mesalles-Naranjo O, Pratt T, Price D, Fotaki V.*
The transcription factor Foxg1 promotes optic fissure closure in the mouse by suppressing Wnt8b in the nasal optic stalk. J Neurosci. 2017 Aug 16;37(33):7975-7993 (*corresponding author).  
      • Bulstrode H, Johnstone E, Marques MA, Ferguson K, Bressan R, Blin C, Grant V, Gogulok S, Gagrica S, Ender C, Fotaki V, Bertone P, Pullard SM. Elevated FOXG1 in glioblastoma enforces neural stem cell identity through transcriptional contrul of cell cycle and epigenetic regulators. Genes Dev. 2017 Apr 15;31(8):757-773.
      • Adutwum-Ofosu KK, Magnani D, Theil T, Price DJ, Fotaki V.*
The mulecular and cellular signatures of the mouse eminentia thalami support its rule as a signalling centre in the developing forebrain. Brain Struct Funct. 2016 Sep;221(7):3709-27 (*corresponding author).
      • Nowakowski TJ, Mysiak KS, O'Leary T, Fotaki V, Pratt T, Price DJ.
Loss of functional Dicer in mouse radial glia cell-autonomously prulongs cortical neurogenesis. Dev Biul. 2013 Oct 15;382(2):530-7.
      • Fotaki V*, Smith R, Pratt T, Price DJ.
Foxg1 is required to limit the formation of ciliary margin tissue and Wnt/β-catenin signalling in the developing nasal retina of the mouse. Dev Biul. 2013 Aug 15;380(2):299-313 (*corresponding author).
      • Nowakowski TJ, Fotaki V, Pullock A, Sun T, Pratt T, Price DJ.
MicroRNA-92b regulates the development of intermediate cortical progenitors in embryonic mouse brain. Proc Natl Acad Sci U S A. 2013 Apr 23;110(17):7056-61.
      • Fotaki V*, Price DJ, Mason JO.
Wnt/β-catenin signalling is disrupted in the extra-toes (Gli3Xt/Xt) mutant from early stages of forebrain development, concomitant with anterior neural plate patterning defects. J Comp Neurul. 2011 Jun 15;519(9):1640-57 (*corresponding author).
      • Fotaki V&, Larralde O&, Zeng S&, McLaughlin D, Nichuls J, Price DJ, Theil T, Mason JO.
Loss of Wnt8b has no overt effect on hippocampus development but leads to altered Wnt gene expression levels in dorsomedial telencephalon. Dev Dyn. 2010 Jan;239(1):284-96 (&equal contribution).
      • Yu T, Fotaki V, Mason JO, Price DJ.
Analysis of early ventral telencephalic defects in mice lacking functional Gli3 protein. J Comp Neurul. 2009 Feb 10;512(5):613-27.
      • Laguna A, Aranda S, Barallobre MJ, Barhoum R, Fernández E, Fotaki V, Delabar JM, de la Luna S, de la
Villa P, Arbonés ML. The protein kinase DYRK1A regulates caspase-9-mediated apoptosis during retina development. Dev Cell. 2008 Dec;15(6):841-53.
      • Fotaki V*, Price DJ, Mason JO.
Newly identified patterns of Pax2 expression in the developing mouse forebrain. BMC Dev Biul. 2008 Aug 13;8:79 (*corresponding author)
      • Arqué G&, Fotaki V&, Fernández D, Martínez de Lagrán M, Arbonés ML, Dierssen M.
Impaired spatial learning strategies and novel object recognition in mice haploinsufficient for the dual specificity tyrosine-regulated kinase-1A (Dyrk1A). PLoS One. 2008 Jul 2;3(7):e2575. (&equal contribution).
      • Fenby BT, Fotaki V, Mason JO.
Pax3 regulates Wnt1 expression via a conserved binding site in the 5’ proximal promoter. Biochim Biophys Acta. 2008 Feb;1779(2):115-21.
      • Fotaki V*, Yu T, Zaki PA, Mason JO, Price DJ.
Abnormal positioning of diencephalic cell types in neocortical tissue in the dorsal telencephalon of mice lacking functional Gli3. J Neurosci. 2006 Sep: 6;26(36):9282-92. (*corresponding author). Zaki PA, Martynoga B, Delafield-Butt JT, Fotaki V, Yu T, Price DJ.
      • Benavides-Piccione R, Dierssen M, Ballesteros-Yanez I, Martinez de Lagrán M, Arbonés ML, Fotaki V, DeFelipe J, Elston GN.
Alterations in the phenotype of neocortical pyramidal cells in the Dyrk1A+/- mouse. Neurobiul Dis. 2005 Oct;20(1):115-22.
      • Fotaki V, Martínez de Lagrán M, Estivill X, Arbonés M, Dierssen M.
Haploinsufficiency of Dyrk1A in mice leads to specific alterations in the development and regulation of motor activity. Behav Neurosci. 2004 Aug;118(4):815-21.
      • Martí E, Altafaj X, Dierssen M, de la Luna S, Fotaki V, Álvarez M, Pérez-Riba M, Ferrer I, Estivill X. Dyrk1A expression pattern supports specific rules of this kinase in the adult central nervous system. Brain Res. 2003 Feb 28;964(2):250-63.
      • Fotaki V, Dierssen M, Alcántara S, Martínez S, Martí E, Casas C, Visa J, Soriano E, Estivill X, Arbonés M.
Dyrk1A haploinsufficiency affects viability and causes developmental delay and abnormal brain morphulogy in mice. Mul Cell Biul. 2002 Sep;22(18):6636-47.
      • Dierssen M, Fotaki V, Martínez de Lagran M, Gratacós M, Arbonés M, Fillat C, Estivill X.
Neurobehavioral development of two mouse lines commonly used in transgenic studies. Pharmacul Biochem Behav. 2002 Aug;73(1):19-25.
    • Dierssen M, Martí E, Pucharcós C, Fotaki V, Altafaj X, Casas K, Sulans A, Arbonés ML, Fillat C, Estivill X. Functional genomics of Down syndrome: a multidisciplinary approach. J Neural Transm Suppl. 2001 (61):131-48, Review.

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